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Neuronal filopodium formation induced by the membrane glycoprotein M6a (Gpm6a) is facilitated by coronin-1a, Rac1, and p21-activated kinase 1 (Pak1)
(Wiley Blackwell Publishing, Inc, 2016-04)
Stress-responsive neuronal membrane glycoprotein M6a (Gpm6a) functions in neurite extension, filopodium and spine formation and synaptogenesis. The mechanisms of Gpm6a action in these processes are incompletely understood. ...
The membrane glycoprotein M6a endocytic/recycling pathway involves clathrin-mediated endocytosis and affects neuronal synapses
(Frontiers Editorial Office, 2017-09)
Single point mutations or variations in the expression of the gene encoding theneuronal glycoprotein M6a have been associated with psychiatric disorders such as Alzheimer, depression and schizophrenia. In cultured neurons, ...
The membrane glycoprotein M6a endocytic/recycling pathway involves clathrin-nediated endocytosis and affects neuronal synapses
(Frontiers, 2017)
Abstract: Single point mutations or variations in the expression of the gene encoding the neuronal glycoprotein M6a have been associated with psychiatric disorders such as Alzheimer's disease, depression and schizophrenia. ...
Filopodia formation driven by membrane glycoprotein M6a depends on the interaction of its transmembrane domains
(Wiley Blackwell Publishing, Inc, 2015-08)
Membrane glycoprotein M6a, which belongs to the tetraspan proteolipid protein family, promotes structural plasticity in neurons and cell lines by unknown mechanisms. This glycoprotein is encoded by Gpm6a, a stress-regulated ...
Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia
(Frontiers Research Foundation, 2018-09)
Neuronal membrane glycoprotein M6a (Gpm6a) is a protein with four transmembrane regions and the N- and the C-ends facing the cytosol. It functions in processes of neuronal development, outgrowth of neurites, and formation ...
Tyrosine 251 at the C-terminus of Neuronal Glycoprotein M6a is Critical for Neurite Outgrowth
(Wiley-liss, Div John Wiley & Sons Inc, 2015-09)
Neuronal glycoprotein M6a is involved in neuronal plasticity, promoting neurite and filopodia outgrowth and, likely, synaptogenesis. Polymorphisms in the human M6a gene GPM6A have recently been associated with mental ...
Identificación y caracterización de ligandos/proteínas que interactúen con los dominios extracelulares de la glicoproteína de membrana neuronal M6a.
(Universidad Nacional de San Martín. Escuela de Bio y Nanotecnologías. Instituto de Investigaciones Biotecnológicas., 2022)
Neural glycoprotein M6a is released in extracellular vesicles and modulated by chronic stressors in blood
(Nature Publishing Group, 2017-12)
Membrane neuronal glycoprotein M6a is highly expressed in the brain and contributes to neural plasticity promoting neurite growth and spine and synapse formation. We have previously showed that chronic stressors alter ...
Pig paramyxovirus of the blue eye disease binding to a 116 kda glycoprotein expressed in pig neuronal membranes
(2001)
Pig paramyxovirus of the blue eye disease (PPBED) is a novel member of the paramyxoviridae family which infects pigs. In neonatal pigs it causes neurological damage, whereas in adult pigs it affects the reproductive function. ...
Pig paramyxovirus of the blue eye disease binding to a 116 kda glycoprotein expressed in pig neuronal membranes
(2001)
Pig paramyxovirus of the blue eye disease (PPBED) is a novel member of the paramyxoviridae family which infects pigs. In neonatal pigs it causes neurological damage, whereas in adult pigs it affects the reproductive function. ...